Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806912 | 0.86 | GRM2 (0.44) | GRM2PARP1FGFR1FGFR2FGFR3 | |
| SCHEMBL6807422 | 0.86 | MALT1 (0.39) | PARP1ALDH1A1CNR1CNR2 | |
| SCHEMBL6804441 | 0.85 | PARP1 (0.55) | PARP1 | |
| SCHEMBL6810590 | 0.81 | GRM2 (0.54) | GRM2LMNAPARP1ALDH1A1 | |
| SCHEMBL6807476 | 0.79 | GRM2 (0.44) | GRM2PARP1ALDH1A1BTKFGFR1 | |
| SCHEMBL6802788 | 0.76 | PARP1 (0.41) | PARP1FGFR1FGFR2FGFR3 | |
| SCHEMBL6587569 | 0.75 | PARP1 (0.39) | LMNAPARP1CNR1PPARABTK | |
| SCHEMBL6801942 | 0.72 | MAPT (0.40) | LMNAPARP1ALDH1A1BTKNPSR1 | |
| SCHEMBL6807418 | 0.72 | PARP1 (0.53) | PARP1 | |
| SCHEMBL6807497 | 0.71 | F7 (0.43) | GRM2PARP1GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |