Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 14/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802788 | 0.90 | PARP1 (0.41) | MALT1FLT3PARP1 | |
| SCHEMBL6804448 | 0.86 | GRM2 (0.38) | PARP1ALDH1A1CNR1CNR2 | |
| SCHEMBL6807418 | 0.86 | PARP1 (0.53) | PARP1 | |
| SCHEMBL6804463 | 0.78 | FLT3 (0.42) | FLT3PARP1ALDH1A1 | |
| SCHEMBL10850115 | 0.77 | ALDH1A1 (0.46) | MALT1ALDH1A1CNR1CNR2 | |
| SCHEMBL6587656 | 0.77 | PARP1 (0.38) | MALT1FLT3PARP1 | |
| SCHEMBL6802778 | 0.75 | PARP1 (0.61) | PARP1 | |
| SCHEMBL6806912 | 0.74 | GRM2 (0.44) | PARP1 | |
| SCHEMBL28451687 | 0.72 | SIRT1 (0.50) | MALT1ALDH1A1 | |
| SCHEMBL6804441 | 0.72 | PARP1 (0.55) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |