Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.38 |
| ▸ | CCR1 | P32246 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810590 | 0.91 | GRM2 (0.54) | GRM2PARP1NPC1RAB9APTGS2 | |
| SCHEMBL6807476 | 0.90 | GRM2 (0.44) | GRM2PARP1NPC1RAB9ACCR1 | |
| SCHEMBL6804448 | 0.86 | GRM2 (0.38) | GRM2PARP1FGFR1FGFR2FGFR3 | |
| SCHEMBL6806910 | 0.84 | PARP1 (0.60) | PARP1ROCK2PTGS2 | |
| SCHEMBL6804457 | 0.82 | PARP1 (0.42) | PARP1PARP2PARP3KMT2AMEN1 | |
| SCHEMBL6807085 | 0.81 | NR3C2 (0.43) | PARP1PARP2PARP3KMT2AMEN1 | |
| SCHEMBL6810628 | 0.80 | PARP1 (0.52) | PARP1PARP2PARP3 | |
| SCHEMBL6810614 | 0.77 | MAP4K4 (0.52) | GRM2PARP1PARP2PARP3NPC1 | |
| SCHEMBL6804463 | 0.75 | FLT3 (0.42) | PARP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6807422 | 0.74 | MALT1 (0.39) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |