Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804144 | 0.90 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2CSNK2A1ALDH1A1TSHR | |
| SCHEMBL6799120 | 0.87 | HDAC7 (0.49) | SMN1; SMN2CSNK2A1ALDH1A1TSHRMCL1 | |
| SCHEMBL6495696 | 0.86 | HSD17B10 (0.58) | HSD17B10SMN1; SMN2CSNK2A1ALDH1A1CYP46A1 | |
| SCHEMBL17394735 | 0.83 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2ALDH1A1HDAC1HDAC6 | |
| SCHEMBL3733709 | 0.81 | HDAC7 (0.60) | HSD17B10SMN1; SMN2CSNK2A1ALDH1A1CYP46A1 | |
| SCHEMBL6804716 | 0.81 | MCL1 (0.46) | HSD17B10SMN1; SMN2CSNK2A1ALDH1A1TSHR | |
| SCHEMBL6639090 | 0.80 | FOLH1 (0.53) | HSD17B10SMN1; SMN2ALDH1A1FOLH1MEN1 | |
| SCHEMBL27999421 | 0.80 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2CSNK2A1CYP46A1MCL1 | |
| SCHEMBL6492370 | 0.80 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2CSNK2A1ALDH1A1CYP46A1 | |
| SCHEMBL6499129 | 0.80 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2CSNK2A1ALDH1A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | HSD17B10 148/4885SMN1; SMN2 1854/4885CSNK2A1 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.