Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799120 | 0.90 | HDAC7 (0.49) | MCL1SMN1; SMN2ALDH1A1TSHRLTB4R2 | |
| SCHEMBL6804144 | 0.87 | HSD17B10 (0.49) | MCL1SMN1; SMN2ALDH1A1TSHRLTB4R2 | |
| SCHEMBL9762624 | 0.87 | MEN1 (0.46) | SMN1; SMN2ALDH1A1LTB4R2SLC16A3AKR1C2 | |
| SCHEMBL6802096 | 0.86 | NPC1 (0.44) | SMN1; SMN2ALDH1A1TSHRLTB4R2PRKAG1 | |
| SCHEMBL8533393 | 0.86 | ALDH1A1 (0.46) | MCL1SMN1; SMN2ALDH1A1LTB4R2SLC16A3 | |
| SCHEMBL10606874 | 0.84 | SLC16A3 (0.50) | SMN1; SMN2ALDH1A1TSHRSLC16A3HSD17B10 | |
| SCHEMBL6803884 | 0.83 | GABRG2 (0.48) | SMN1; SMN2ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL6498971 | 0.83 | HDAC7 (0.57) | MCL1SMN1; SMN2ALDH1A1PRKAB2PRKAG1 | |
| SCHEMBL6809087 | 0.82 | CYP2C8 (0.49) | ALDH1A1AKR1C2HSD17B10KDM4E | |
| SCHEMBL6804641 | 0.81 | HSD17B10 (0.49) | MCL1SMN1; SMN2ALDH1A1TSHRLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | MCL1 1945/4885SMN1; SMN2 1854/4885ALDH1A1 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.