Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 5/20 | 0.50 |
| ▸ | GABRD | O14764 | 5/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.50 |
| ▸ | GABRE | P78334 | 5/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738366 | 0.78 | TSHR (0.76) | TSHRLMNAMAPTNPC1RAB9A | |
| Iodide SCHEMBL30804629 | 0.76 | TSHR (0.73) | TSHRLMNAMAPTNPC1RAB9A | |
| SCHEMBL28471286 | 0.76 | TSHR (0.73) | TSHRLMNAMAPTNPC1RAB9A | |
| SCHEMBL11392461 | 0.76 | TSHR (0.73) | TSHRLMNAMAPTNPC1RAB9A | |
| Iodide SCHEMBL28598177 | 0.76 | TSHR (0.73) | TSHRLMNAMAPTNPC1RAB9A | |
| SCHEMBL11392466 | 0.76 | TSHR (0.73) | TSHRLMNAMAPTNPC1RAB9A | |
| SCHEMBL11604916 | 0.75 | PTPRC (0.62) | PTPRCTSHRLMNAMAPTMAOB | |
| SCHEMBL2345035 | 0.74 | PTPRC (0.54) | PTPRCTSHRLMNAMAPTNPC1 | |
| SCHEMBL1471565 | 0.73 | MAPT (0.46) | TSHRMAPTMAOBNPC1RAB9A | |
| SCHEMBL10840844 | 0.73 | TSHR (0.61) | PTPRCTSHRLMNAGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266774-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-30 | — | — | US | disclosed |
| US-6770667-B1 | N-((IMIDAZOLYL)-PHENYL)-FLUORENE-1-CARBOXAMIDE DERIVATIVES; 5-HYDROXYTRYPTAMINE (5-HT) ANTAGONISTS; PSYCHOLOGICAL, NERVOUS SYSTEM, EATING, BRAIN AND SLEEP DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
| EP-1216240-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001025229-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266774-A1 | Amide compounds | TPH1, HTR1A, HTR5A | PTPRC 4427/4885TSHR 112/4885LMNA 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.