Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5438031 | 1.00 | CYP1A2 (0.39) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5436252 | 1.00 | CYP1A2 (0.39) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5437305 | 1.00 | CYP1A2 (0.39) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL6805031 | 1.00 | CYP1A2 (0.39) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL14459031 | 1.00 | CYP1A2 (0.39) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5441803 | 1.00 | CYP1A2 (0.39) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5437213 | 1.00 | CYP1A2 (0.39) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL16306576 | 0.90 | CYP1A2 (0.44) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL15308541 | 0.90 | CYP1A2 (0.44) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL15894815 | 0.84 | CYP1A2 (0.40) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132636-A1 | Pharmaceutical uses for alpha2delta ligands | DOOLEY DAVID JAMES (US) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132636-A1 | Pharmaceutical uses for alpha2delta ligands | ADRA1D, OPRD1, ADRA1A | CYP1A2 438/4885USP2 4293/4885ALDH1A1 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.