SCHEMBL6805430

SCHEMBL6805430

CC(=O)Cc1ccccc1CC(C)=O

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.57
▸ AKR1B1 P15121 2/20 0.46
▸ CYP3A4 P08684 1/20 0.45
▸ ALDH1A1 P00352 4/20 0.44
▸ LMNA P02545 2/20 0.42
▸ IAPP P10997 1/20 0.42
▸ POLB P06746 2/20 0.41
▸ MAPT P10636 2/20 0.41
▸ GAA P10253 1/20 0.41
▸ CES2 O00748 2/20 0.40
▸ CES1 P23141 2/20 0.40
▸ GABRA1 P14867 1/20 0.40
▸ GABRB2 P47870 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ CTBP2 P56545 1/20 0.39
▸ MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL10992898 0.97 L3MBTL1 (0.60) L3MBTL1AKR1B1CYP3A4ALDH1A1LMNA
SCHEMBL7150622 0.93 L3MBTL1 (0.52) L3MBTL1AKR1B1CYP3A4ALDH1A1LMNA
SCHEMBL80263 0.91 L3MBTL1 (0.50) L3MBTL1AKR1B1CYP3A4ALDH1A1LMNA
SCHEMBL3687049 0.91 AKR1B1 (0.61) L3MBTL1AKR1B1ALDH1A1LMNAMAPT
SCHEMBL29676820 0.91 AKR1B1 (0.61) L3MBTL1AKR1B1ALDH1A1LMNAMAPT
SCHEMBL11283717 0.89 L3MBTL1 (0.49) L3MBTL1AKR1B1CYP3A4ALDH1A1LMNA
SCHEMBL27734152 0.89 L3MBTL1 (0.53) L3MBTL1AKR1B1CYP3A4ALDH1A1LMNA
SCHEMBL13369550 0.89 L3MBTL1 (0.49) L3MBTL1AKR1B1CYP3A4ALDH1A1LMNA
SCHEMBL8109115 0.89 L3MBTL1 (0.49) L3MBTL1AKR1B1CYP3A4ALDH1A1LMNA
SCHEMBL21100153 0.87 L3MBTL1 (0.47) L3MBTL1AKR1B1CYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2023-10-19 — — US disclosed
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2023-10-19 — — US disclosed
CN-108109963-B Display unit, method of manufacturing the same, and electronic apparatus 索尼公司 2022-07-01 — — CN disclosed
CN-104425624-B Electronic device, image display device and the substrate for constituting image display device 索尼公司 2019-06-07 — — CN disclosed
CN-108109963-A Display unit and its manufacturing method and electronic equipment 索尼公司 2018-06-01 — — CN disclosed
WO-2017205309-A1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME CORP. (US) 2017-11-30 — — WO disclosed
CN-106952929-A Display unit and its manufacture method and electronic equipment 索尼公司 2017-07-14 — — CN disclosed
CN-103972263-A Display unit, method of manufacturing the same, and electronic apparatus SONY CORP 2014-08-06 — — CN disclosed
US-6833373-B1 N-(3-hydroxy-5-((1,4,5,6-tetrahydro-5-hydroxy-2-pyrimidinyl) -amino)-benzoyl)glycyl-3-(3-bromo-5-chloro-2-hydroxyphenyl)-b-alanine and tamoxifen; breast cancer G.D. SEARLE & CO. 2004-12-21 — — US disclosed
US-4463171-A BACTERICIDES SANRAKU-OCEAN CO., LTD. (JP) 1984-07-31 — — US disclosed
EP-0017970-B1 NOVEL BETA-LACTAM DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF SANRAKU-OCEAN CO., LTD. (JP) 1982-07-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES NUDT1, PNP, ATIC L3MBTL1 3712/4885AKR1B1 1392/4885CYP3A4 1370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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