Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 16/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805769 | 0.88 | KDM4E (0.37) | PARP1 | |
| SCHEMBL6584637 | 0.87 | PARP1 (0.39) | PARP1DHODH | |
| SCHEMBL6805760 | 0.78 | PARP1 (0.51) | PARP1DHODH | |
| SCHEMBL6806325 | 0.73 | PARP1 (0.62) | PARP1DHODHAURKB | |
| SCHEMBL29411925 | 0.70 | PARP1 (0.72) | PARP1DHODHAURKB | |
| SCHEMBL6806945 | 0.68 | PARP1 (0.60) | PARP1DHODHAURKB | |
| SCHEMBL6805407 | 0.67 | PARP1 (0.60) | PARP1DHODHAURKB | |
| SCHEMBL6803959 | 0.66 | PARP1 (0.65) | PARP1DHODHAURKB | |
| SCHEMBL6802028 | 0.66 | PARP1 (0.66) | PARP1DHODHAURKB | |
| SCHEMBL29411891 | 0.65 | PARP1 (1.00) | PARP1DHODHAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |