Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798547 | 0.80 | HTR6 (0.56) | HTR6ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL10775490 | 0.78 | TAAR1 (0.55) | SLC6A4SLC6A2TAAR1MAOASLC6A3 | |
| SCHEMBL6540600 | 0.78 | SLC6A4 (0.74) | SLC6A4TAAR1 | |
| SCHEMBL8865817 | 0.77 | HTR6 (0.74) | HTR6ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6913555 | 0.77 | HTR6 (1.00) | HTR6ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL28541778 | 0.76 | HTR6 (0.77) | HTR6ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL931939 | 0.76 | HTR6 (0.77) | HTR6ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7176841 | 0.74 | HTR6 (0.74) | HTR6ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL31352974 | 0.73 | HTR6 (0.77) | HTR6ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL1412238 | 0.72 | ADRA1D (0.55) | SLC6A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | HTR6 689/4885SLC6A4 2109/4885ABCC9 1596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.