SCHEMBL931939

SCHEMBL931939

COc1ccc(S(=O)(=O)c2ccccc2OC)cc1

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.77
PKM P14618 2/20 0.62
MMP2 P08253 12/20 0.57
MMP12 P39900 12/20 0.57
MMP8 P22894 11/20 0.57
MMP13 P45452 11/20 0.57
MMP14 P50281 11/20 0.57
MMP16 P51512 11/20 0.57
MMP9 P14780 11/20 0.57
MMP3 P08254 8/20 0.54
MMP1 P03956 5/20 0.54
ADAM17 P78536 1/20 0.54
GAA P10253 1/20 0.53
ABCC9 O60706 1/20 0.52
ABCC8 Q09428 1/20 0.52
KCNJ11 Q14654 1/20 0.52
KCNJ8 Q15842 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6913555 0.87 HTR6 (1.00) HTR6PKMMMP2MMP12MMP8
SCHEMBL28541778 0.86 HTR6 (0.77) HTR6GAAABCC9ABCC8KCNJ11
SCHEMBL7176841 0.84 HTR6 (0.74) HTR6PKMMMP2MMP12MMP8
SCHEMBL8865817 0.84 HTR6 (0.74) HTR6ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL31352974 0.82 HTR6 (0.77) HTR6PKMGAAABCC9ABCC8
SCHEMBL8933453 0.82 PKM (0.62) HTR6PKMMMP2MMP12MMP8
SCHEMBL10592283 0.81 GAA (0.61) HTR6PKMMMP2MMP12MMP8
SCHEMBL11114971 0.81 HTR6 (0.65) HTR6PKMMMP2MMP12MMP8
SCHEMBL4593428 0.80 PKM (0.55) HTR6PKMMMP2MMP12MMP8
SCHEMBL8865874 0.80 HTR6 (0.68) HTR6PKMABCC9ABCC8KCNJ11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117098671-A Compositions and methods for sensitizing thermal media 索理思科技开曼公司 2023-11-21 CN disclosed
US-11529819-B2 Recording material and compound NIPPON SODA CO., LTD. (JP) 2022-12-20 US disclosed
CN-114667279-A Heat-sensitive recording material containing non-phenol color developer 索理思科技开曼公司 2022-06-24 CN disclosed
CN-110709255-B Recording material and compound 日本曹达株式会社 2021-08-06 CN disclosed
US-20210060994-A1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS BASF SE (DE) 2021-03-04 US disclosed
EP-3263553-B1 CRYSTALLINE MODIFICATION OF N-(2-(3-PHENYLUREIDO)PHENYL)BENZENESULFONAMIDE AND RECORDING MATERIAL USING SAME NIPPON SODA CO (JP) 2020-12-09 EP disclosed
EP-3636446-A1 RECORDING MATERIAL AND COMPOUND Nippon Soda Co., Ltd. (JP) 2020-04-15 EP disclosed
US-20200086669-A1 RECORDING MATERIAL AND COMPOUND NIPPON SODA CO., LTD. (JP) 2020-03-19 US disclosed
CN-110709255-A Recording material and compound 日本曹达株式会社 2020-01-17 CN disclosed
EP-2484663-B1 PHENOLIC COMPOUND AND RECORDING MATERIAL NIPPON SODA CO (JP) 2019-07-17 EP disclosed
US-20060063669-A1 Recording material comprising diphenyl sulfone derivative and novel diphenyl sulfone derivative compound NIPPON SODA CO., LTD. (JP) 2006-03-23 US disclosed
EP-1557408-A1 RECORDING MATERIAL COMPRISING DIPHENYL SULFONE DERIVATIVE AND NOVEL DIPHENYL SULFONE DERIVATIVE COMPOUND NIPPON SODA CO., LTD. (JP) 2005-07-27 EP disclosed
US-20050148468-A1 Recording material and recording sheet NIPPON SODA CO., LTD. (JP) 2005-07-07 US disclosed
US-20050096222-A1 For use in recording materials using a color developing dye, such as thermal sensitive recording material and pressure sensitive copying material, storage stability NIPPON SODA CO., LTD. (JP) 2005-05-05 US disclosed
US-20040198603-A1 Recording material and recording sheet NIPPON SODA CO., LTD. (JP) 2004-10-07 US disclosed
EP-1375182-A1 RECORDING MATERIAL AND RECORDING SHEET NIPPON SODA CO., LTD. (JP) 2004-01-02 EP disclosed
EP-0860429-B1 DIPHENYL SULFONE CROSSLINKING TYPE COMPOUNDS AND RECORDING MATERIALS USING THEM NIPPON SODA CO (JP) 2001-12-12 EP disclosed
US-6143060-A EXCELLENT IN THE STORAGE STABILITY OF DEVELOPED IMAGES, PARTICULARLY THE RESISTANCE THEREOF TO PLASTICIZERS NIPPON SODA CO., LTD. (JP) 2000-11-07 US disclosed
US-6037308-A HIGH RECORDED IMAGE PRESERVABILITY NIPPON SODA CO., LTD. (JP) 2000-03-14 US disclosed
EP-0906908-A1 TRIAZINE DERIVATIVES AND RECORDING MATERIALS PREPARED THEREFROM NIPPON SODA CO., LTD. (JP) 1999-04-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11529819-B2 Recording material and compound H1-0, DOT1L, H1-4 HTR6 1912/4885PKM 3977/4885MMP2 2122/4885
US-20200086669-A1 RECORDING MATERIAL AND COMPOUND H1-0, DOT1L, H1-4 HTR6 1912/4885PKM 3977/4885MMP2 2122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.