Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 4/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137097 | 1.00 | KHK (0.44) | KHKRIPK1BDKRB1NR3C1HDAC1 | |
| SCHEMBL7135489 | 0.90 | HDAC1 (0.40) | RIPK1BDKRB1NR3C1HDAC1HDAC6 | |
| SCHEMBL6801682 | 0.90 | HDAC1 (0.40) | RIPK1BDKRB1NR3C1HDAC1HDAC6 | |
| SCHEMBL6801089 | 0.89 | KHK (0.39) | KHKNR3C1 | |
| SCHEMBL6804988 | 0.87 | KMT2A (0.44) | NR3C1KMT2A | |
| SCHEMBL6800502 | 0.87 | KMT2A (0.44) | NR3C1KMT2A | |
| SCHEMBL6806651 | 0.87 | KMT2A (0.44) | NR3C1KMT2A | |
| SCHEMBL6810208 | 0.84 | KHK (0.41) | KHKRIPK1BDKRB1NR3C1HSD17B2 | |
| SCHEMBL7135350 | 0.84 | HSD17B10 (0.48) | KHKRIPK1KMT2AHPGDMAPT | |
| SCHEMBL6806190 | 0.84 | HSD17B10 (0.48) | KHKRIPK1KMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029875-A1 | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2004-02-12 | — | — | US | claimed |
| US-20040029875-A1 | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2004-02-12 | — | — | US | disclosed |
| EP-1324998-A1 | NOVEL AMINOTRIAZOLONE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030923-A1 | NOVEL AMINOTRIAZOLONE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029875-A1 | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | ADORA1, AASDHPPT, AADAT | KHK 1013/4885RIPK1 4643/4885BDKRB1 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.