Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135489 | 1.00 | HDAC1 (0.40) | HDAC1HDAC6HDAC8BDKRB1PDE4B | |
| SCHEMBL6805857 | 0.90 | KHK (0.44) | HDAC1HDAC6BDKRB1RIPK1MAPT | |
| SCHEMBL7137097 | 0.90 | KHK (0.44) | HDAC1HDAC6BDKRB1RIPK1MAPT | |
| SCHEMBL6805271 | 0.90 | BDKRB1 (0.38) | HDAC1HDAC6HDAC8BDKRB1PDE4B | |
| SCHEMBL6801089 | 0.90 | KHK (0.39) | NR3C1 | |
| SCHEMBL6806651 | 0.88 | KMT2A (0.44) | PTGDR2NR3C1 | |
| SCHEMBL6800502 | 0.88 | KMT2A (0.44) | PTGDR2NR3C1 | |
| SCHEMBL6804988 | 0.88 | KMT2A (0.44) | PTGDR2NR3C1 | |
| Hydrochloric Acid SCHEMBL6811362 | 0.84 | CRACR2A (0.39) | BDKRB1MAPT | |
| SCHEMBL7087405 | 0.84 | PKM (0.58) | HDAC1HDAC6HDAC8RIPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029875-A1 | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2004-02-12 | — | — | US | claimed |
| EP-1324998-A1 | NOVEL AMINOTRIAZOLONE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2003-07-09 | — | — | EP | claimed |
| WO-2002030923-A1 | NOVEL AMINOTRIAZOLONE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-04-18 | — | — | WO | claimed |
| US-20040029875-A1 | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029875-A1 | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | ADORA1, AASDHPPT, AADAT | HDAC1 3236/4885HDAC6 2279/4885HDAC8 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.