Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.44 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7108565 | 0.85 | BCHE (0.41) | ACHEBCHEASAH1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5852870 | 0.78 | SOAT1 (0.44) | ASAH1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5853770 | 0.78 | SOAT1 (0.44) | ASAH1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5852948 | 0.76 | SOAT1 (0.42) | ACHEBCHEASAH1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5855392 | 0.75 | NPSR1 (0.39) | ACHEBCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6865136 | 0.73 | ACHE (0.39) | ACHEBCHESIGMAR1CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL5855467 | 0.72 | KMT2A (0.36) | ACHEBCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5853837 | 0.71 | NPC1 (0.39) | ACHEBCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5854939 | 0.70 | MAPT (0.36) | ACHEBCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5852098 | 0.70 | MEN1 (0.44) | ACHEBCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |