Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525635 | 0.70 | MAOB (0.43) | MAOAMAOBLTA4HRAB9ASMN1; SMN2 | |
| SCHEMBL6991894 | 0.68 | NPC1 (0.46) | ALDH1A1MAOAMAOBMPOLTA4H | |
| SCHEMBL7931809 | 0.63 | CALM1 (0.44) | CALM1MAOAMAOBLTA4HHTR2A | |
| SCHEMBL6055305 | 0.62 | CALM1 (0.38) | CALM1ALDH1A1MAOAMAOBLTA4H | |
| SCHEMBL23880288 | 0.62 | CALM1 (0.55) | CALM1ALDH1A1MAOAMAOBLTA4H | |
| SCHEMBL1498780 | 0.62 | CALM1 (0.55) | CALM1ALDH1A1MAOAMAOBLTB4R | |
| SCHEMBL2820256 | 0.62 | CALM1 (0.73) | CALM1ALDH1A1MAOBLTA4HHTR2A | |
| Diphenylmethane SCHEMBL14763944 | 0.61 | CALM1 (1.00) | CALM1ALDH1A1MAOBLTA4HLOXL2 | |
| Diphenylmethane SCHEMBL3792579 | 0.61 | CALM1 (1.00) | CALM1ALDH1A1MAOBLTA4HLOXL2 | |
| Diphenylmethane SCHEMBL4361124 | 0.61 | CALM1 (1.00) | CALM1ALDH1A1MAOBLTA4HLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006230-A1 | Useful as inhibitors of serine proteases; for therapy and prophylaxis of thrombotic conditions including coronary artery and cerebrovascular diseases | PHARMACIA CORPORATION | 2004-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006230-A1 | Useful as inhibitors of serine proteases; for therapy and prophylaxis of thrombotic conditions including coronary artery and cerebrovascular diseases | PRSS1, SERPINC1, SERPINE1 | CALM1 2415/4885ALDH1A1 3078/4885MAOA 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.