Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27269583 | 0.91 | — | — | |
| SCHEMBL4296118 | 0.85 | GUSB (0.36) | KDM4ECYP2D6ALDH1A1CYP1A2 | |
| SCHEMBL1404051 | 0.81 | KDM4E (0.35) | KDM4EGLAIDO1HTR1ACHRM2 | |
| SCHEMBL3248168 | 0.81 | SLC6A3 (0.41) | SLC6A3 | |
| SCHEMBL8767704 | 0.81 | KDM4E (0.35) | KDM4EGLAIDO1HTR1ACHRM2 | |
| SCHEMBL22996895 | 0.80 | MC4R (0.34) | KDM4EGLAIDO1HTR1ACHRM2 | |
| SCHEMBL1650151 | 0.79 | SLC6A3 (0.40) | SLC6A3 | |
| SCHEMBL23045241 | 0.77 | RAB9A (0.43) | SLC6A3 | |
| SCHEMBL12706352 | 0.77 | — | — | |
| SCHEMBL16972740 | 0.76 | CHRM2 (0.34) | KDM4EIDO1HTR1ACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030087981-A1 | Floor finish compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-08 | — | — | US | claimed |
| US-6197844-B1 | Floor finish compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2001-03-06 | — | — | US | claimed |
| US-8030327-B2 | 3-[1-(2-chlorophenyl)ethoxy]-5-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxyamide; polo like kinase inhibitor; antitumor and anticarcinogenic agent; mitotic phase (M phase) of the cell cycle | MDS K.K. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-20080103136-A1 | Novel Fused Imidazole Derivative | MSD K.K. (JP) | 2008-05-01 | — | — | US | disclosed |
| US-6780472-B2 | POLYFUNCTIONAL ISOCYANURATE HAVING AT LEAST THREE TERMINAL REACTIVE GROUPS REACTED WITH HYDROXYALKYL ACRYLATE AND TERTIARY AMINE ALCOHOL | 3M INNOVATIVE PROPERTIES COMPANY | 2004-08-24 | — | — | US | disclosed |
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |
| US-20030087981-A1 | Floor finish compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-08 | — | — | US | disclosed |
| US-6197844-B1 | Floor finish compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2001-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103136-A1 | Novel Fused Imidazole Derivative | HRH4, H1-4, H1-3 | KDM4E 1299/4885GLA 3946/4885IDO1 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.