Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 11/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746357 | 0.81 | DRD2 (0.38) | DRD3 | |
| SCHEMBL3587428 | 0.80 | MC4R (0.40) | CHRM2CHRM4CHRM5ADRA2AADORA3 | |
| SCHEMBL6745237 | 0.80 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL16972741 | 0.79 | CHRM2 (0.37) | CHRM2CHRM4CHRM5ADRA2AADORA3 | |
| SCHEMBL5709265 | 0.79 | SLC6A3 (0.39) | SLC6A3 | |
| SCHEMBL6744360 | 0.78 | ALDH1A1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL13881902 | 0.78 | MC4R (0.36) | CHRM2CHRM4CHRM5ADRA2AADORA3 | |
| SCHEMBL7330270 | 0.77 | SLC6A3 (0.38) | SLC6A3 | |
| SCHEMBL4396753 | 0.76 | SLC6A3 (0.32) | CHRM2CHRM4CHRM5ADRA2AADORA3 | |
| SCHEMBL6806038 | 0.76 | KDM4E (0.33) | CHRM2CHRM4CHRM5ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015114352-A1 | COMPOSITION | CHEMSENTI LIMITED (GB) | 2015-08-06 | — | — | WO | disclosed |