Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LIG1 | P18858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 3/20 | 0.42 |
| ▸ | FNTB | P49356 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219753 | 0.88 | FNTA (0.53) | MAPTLMNAHTTRAB9AMEN1 | |
| SCHEMBL6219974 | 0.85 | ALDH1A1 (0.47) | MAPTLMNAHTTHPGDRAB9A | |
| SCHEMBL6219202 | 0.81 | KMT2A (0.42) | MAPTLMNARAB9AKMT2ANPC1 | |
| SCHEMBL6219371 | 0.81 | KMT2A (0.47) | MAPTLMNAHTTHPGDRAB9A | |
| SCHEMBL6220407 | 0.80 | MAPK1 (0.51) | MAPTLMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL6220270 | 0.78 | SRD5A2 (0.45) | MAPTHTTHPGDRAB9ANPC1 | |
| SCHEMBL6799716 | 0.76 | PBRM1 (0.56) | MAPTLMNANPC1FNTAFNTB | |
| SCHEMBL16973593 | 0.74 | FNTA (0.41) | MAPTRAB9ANPC1FNTAFNTB | |
| SCHEMBL20377223 | 0.73 | RAB9A (0.76) | MAPTLMNAHTTESR1ESR2 | |
| SCHEMBL28070421 | 0.72 | BAZ2B (0.38) | MAPTLMNAHTTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152897-A1 | Synthesis of indolizines | SYNTA PHARMACEUTICALS CORP. (US) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152897-A1 | Synthesis of indolizines | INMT, IDO1, IDO2 | MAPT 3118/4885LMNA 2205/4885HTT 2785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.