Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 7/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.55 |
| ▸ | STS | P08842 | 12/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457816 | 0.95 | HSD17B2 (0.60) | HSD17B2HSD17B1STSCA1CA2 | |
| SCHEMBL6806433 | 0.91 | HSD17B2 (0.56) | HSD17B2HSD17B1STSCA1CA2 | |
| SCHEMBL6802010 | 0.81 | STS (0.60) | HSD17B2HSD17B1STSCA1CA2 | |
| SCHEMBL6796131 | 0.74 | HSD17B2 (0.91) | HSD17B2HSD17B1 | |
| SCHEMBL9451393 | 0.74 | CA2 (0.66) | HSD17B2HSD17B1STSCA1CA2 | |
| SCHEMBL6800441 | 0.73 | STS (0.57) | STSCA1CA2CA9CA12 | |
| SCHEMBL6799571 | 0.72 | CA1 (0.61) | HSD17B2HSD17B1STSCA1CA2 | |
| Hydrochloric Acid SCHEMBL9451392 | 0.72 | CA2 (0.63) | HSD17B2HSD17B1STSCA1CA2 | |
| SCHEMBL6802989 | 0.72 | STS (0.64) | STSCA1CA2CA9CA12 | |
| SCHEMBL31530329 | 0.71 | HTT (0.59) | HSD17B2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |