Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.49 |
| ▸ | STS | P08842 | 7/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802010 | 0.89 | STS (0.60) | CA1CA2CA9CA12STS | |
| SCHEMBL6801736 | 0.87 | CA1 (0.65) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL6800382 | 0.82 | MCHR1 (0.55) | HSD17B1HSD17B2PGR | |
| SCHEMBL6799672 | 0.81 | NSD2 (0.64) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL6795598 | 0.81 | MEN1 (0.60) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL6799562 | 0.80 | CYP19A1 (0.63) | CA1CA2CA9CYP19A1STS | |
| SCHEMBL2233585 | 0.79 | CA2 (0.69) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL9451286 | 0.78 | CA2 (1.00) | CA1CA2CA9CA12CYP19A1 | |
| SCHEMBL6794239 | 0.78 | CA2 (0.52) | CA1CA2CA9CA12PGR | |
| Water SCHEMBL11222637 | 0.76 | PGR (0.50) | CA1CA2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |