Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 14/20 | 0.60 |
| ▸ | CA2 | P00918 | 6/20 | 0.58 |
| ▸ | CA9 | Q16790 | 6/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799571 | 0.89 | CA1 (0.61) | STSCA2CA9CA1CA12 | |
| SCHEMBL7457816 | 0.86 | HSD17B2 (0.60) | STSCA2CA9CA1CA12 | |
| SCHEMBL6799997 | 0.83 | STS (0.62) | STSCA2CA9CA1CA12 | |
| SCHEMBL6806433 | 0.82 | HSD17B2 (0.56) | STSCA2CA9CA1CA12 | |
| SCHEMBL6806436 | 0.81 | HSD17B2 (0.55) | STSCA2CA9CA1CA12 | |
| SCHEMBL6800782 | 0.80 | STS (0.56) | STS | |
| SCHEMBL6800441 | 0.78 | STS (0.57) | STSCA2CA9CA1CA12 | |
| SCHEMBL6806168 | 0.78 | STS (0.56) | STSCA2CA9CA1CA12 | |
| SCHEMBL6806574 | 0.78 | HSD17B1 (0.65) | CA2CA1HSD17B1HSD17B2 | |
| SCHEMBL6802989 | 0.76 | STS (0.64) | STSCA2CA9CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |