Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810757 | 0.85 | KDM4E (0.43) | — | |
| SCHEMBL6810808 | 0.85 | GRIN2B (0.47) | — | |
| SCHEMBL27608575 | 0.82 | CCR3 (0.53) | CCR3KCNH2HRH3ALDH1A1 | |
| SCHEMBL11135368 | 0.82 | KCNH2 (0.56) | KCNH2HRH3 | |
| SCHEMBL7405653 | 0.82 | CCR3 (0.51) | CCR3KCNH2HRH3 | |
| SCHEMBL9735226 | 0.80 | CCR3 (0.60) | CCR3KCNH2HRH3 | |
| SCHEMBL27604086 | 0.79 | CCR3 (0.49) | CCR3KCNH2HRH3 | |
| SCHEMBL6810106 | 0.77 | FAAH (0.51) | CCR3KCNH2 | |
| SCHEMBL133620 | 0.77 | CCR3 (0.61) | CCR3ALDH1A1 | |
| SCHEMBL278451 | 0.76 | HRH3 (0.71) | CCR3KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409477-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003010159-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-02-06 | — | — | WO | disclosed |