Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27604086 | 0.82 | CCR3 (0.49) | CCR3KCNH2HRH3PRMT3CARM1 | |
| SCHEMBL6806817 | 0.82 | CCR3 (0.55) | CCR3KCNH2HRH3 | |
| SCHEMBL11135368 | 0.82 | KCNH2 (0.56) | KCNH2HRH3 | |
| SCHEMBL27608575 | 0.79 | CCR3 (0.53) | CCR3KCNH2HRH3 | |
| SCHEMBL6810106 | 0.77 | FAAH (0.51) | CCR3KCNH2 | |
| SCHEMBL133620 | 0.77 | CCR3 (0.61) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL27604084 | 0.77 | KCNH2 (0.53) | KCNH2HRH3 | |
| SCHEMBL278451 | 0.76 | HRH3 (0.71) | CCR3KCNH2HRH3 | |
| SCHEMBL27590394 | 0.75 | FAAH (0.49) | CCR3KCNH2HRH3CARM1PRMT6 | |
| SCHEMBL9432473 | 0.74 | MEN1 (0.58) | CCR3PRMT3CARM1PRMT6PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869792-A4 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 1999-09-22 | — | — | EP | disclosed |
| EP-0869792-A2 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023216-A1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |