Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.46 |
| ▸ | HTR2B | P41595 | 4/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810929 | 0.91 | GRIN2B (0.56) | ADRA2AHTR2AADRA1AGRIN2BHTR2B | |
| SCHEMBL6810947 | 0.80 | GRIN1 (0.61) | KMT2AGRIN2BGRIN1GRIN2DHTR1A | |
| SCHEMBL27590394 | 0.79 | FAAH (0.49) | FAAHKMT2ACCR3GRIN2BGRIN1 | |
| SCHEMBL4577623 | 0.78 | GRIN1 (0.54) | GRIN2BGRIN1GRIN2DHTR1AGRIN2A | |
| SCHEMBL11135368 | 0.77 | KCNH2 (0.56) | ADRA2AHTR2AADRA1AGRIN2BHTR2B | |
| SCHEMBL7405653 | 0.77 | CCR3 (0.51) | CCR3KCNH2 | |
| SCHEMBL6806817 | 0.77 | CCR3 (0.55) | CCR3KCNH2 | |
| SCHEMBL6810716 | 0.77 | MEN1 (0.47) | KMT2ACCR3HTR2A | |
| SCHEMBL27608575 | 0.75 | CCR3 (0.53) | CCR3GRIN2BGRIN1KCNH2 | |
| SCHEMBL27604086 | 0.75 | CCR3 (0.49) | CCR3ADRA2AHTR2AADRA1AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409477-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003010159-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-02-06 | — | — | WO | disclosed |