Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444222 | 0.90 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL30849526 | 0.84 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL3232775 | 0.81 | HDAC1 (0.49) | SMN1; SMN2 | |
| SCHEMBL29655446 | 0.81 | NPC1 (0.59) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL2982740 | 0.81 | NPC1 (0.59) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL3224292 | 0.81 | HDAC1 (0.48) | SMN1; SMN2 | |
| SCHEMBL30163690 | 0.81 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL1733957 | 0.80 | PDK1 (0.58) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL17576123 | 0.80 | TDP1 (0.47) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7898674 | 0.79 | NPY5R (0.59) | ALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |