Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 3/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 4/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | F9 | P00740 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807930 | 0.91 | F10 (0.60) | POLBSMN1; SMN2F10PRSS1F9 | |
| SCHEMBL6808022 | 0.83 | LMNA (0.49) | SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL6807765 | 0.81 | F10 (0.62) | POLBF10PRSS1F9PLAU | |
| SCHEMBL6802380 | 0.81 | HTT (0.47) | POLBSMN1; SMN2KMT2AF10F9 | |
| SCHEMBL895009 | 0.79 | PARP1 (0.63) | PARP1PARP10SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29761319 | 0.79 | PARP1 (0.63) | PARP1PARP10SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6807561 | 0.76 | TP53 (0.63) | POLBSMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL6808206 | 0.75 | NPC1 (0.74) | POLBPARP1PARP10SMN1; SMN2KMT2A | |
| SCHEMBL6802349 | 0.74 | F9 (0.49) | F10F9PLAU | |
| SCHEMBL5163848 | 0.74 | F10 (0.55) | POLBSMN1; SMN2KMT2AF10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | MERCK PATENT GMBH (DE) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | RCOR3, F2, NCOR2 | POLB 3408/4885PARP1 686/4885PARP10 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.