Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802349 | 0.90 | F9 (0.49) | — | |
| SCHEMBL6806834 | 0.83 | POLB (0.54) | NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6807930 | 0.81 | F10 (0.60) | SMN1; SMN2 | |
| SCHEMBL2545099 | 0.80 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6802380 | 0.80 | HTT (0.47) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL1127877 | 0.78 | ALDH1A1 (0.59) | RAB9AMEN1KMT2A | |
| SCHEMBL6807561 | 0.73 | TP53 (0.63) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4611142 | 0.73 | SMN1; SMN2 (0.56) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10599853 | 0.72 | MEN1 (0.79) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6807765 | 0.71 | F10 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | MERCK PATENT GMBH (DE) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | RCOR3, F2, NCOR2 | LMNA 436/4885NPC1 2490/4885RAB9A 4524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.