Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | CES2 | O00748 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196396 | 0.88 | MAPK1 (0.68) | VCAM1MAPK1CES2ALDH1A1BCL2L1 | |
| SCHEMBL27946265 | 0.88 | PARP1 (0.56) | VCAM1MAPK1CES2ALDH1A1BCL2L1 | |
| SCHEMBL2433562 | 0.84 | CASP6 (0.66) | PARP1LMNAPOLBCASP6 | |
| SCHEMBL8349696 | 0.84 | PARP1 (0.67) | ALDH1A1PARP1LMNAGAAPOLB | |
| SCHEMBL11014183 | 0.82 | MAPK1 (0.73) | VCAM1MAPK1CES2ALDH1A1CDC25B | |
| SCHEMBL144666 | 0.81 | MAPK1 (0.77) | VCAM1MAPK1CES2ALDH1A1CES1 | |
| SCHEMBL6806851 | 0.81 | MAPK1 (0.77) | VCAM1MAPK1CES2ALDH1A1CES1 | |
| SCHEMBL27605479 | 0.81 | CASP6 (0.62) | VCAM1MAPK1CES2ALDH1A1CDC25B | |
| Carbamic Acid SCHEMBL28096989 | 0.81 | MAPK1 (0.62) | VCAM1MAPK1CES2ALDH1A1CDC25B | |
| Carbamic Acid SCHEMBL28101135 | 0.81 | MAPK1 (0.62) | VCAM1MAPK1CES2ALDH1A1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | AJINOMOTO CO. INC | 2004-01-01 | — | — | US | claimed |
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | AJINOMOTO CO. INC | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | NFKBIA, IKBKB, CHUK | VCAM1 5/4885MAPK1 783/4885CES2 2486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.