Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6511659 | 0.98 | ENPP2 (0.46) | ENPP2TGM2IDO1KDM4EALDH1A1 | |
| SCHEMBL2017578 | 0.81 | CA12 (0.64) | ENPP2TGM2ALDH1A1CYP3A4HPGD | |
| SCHEMBL11715148 | 0.80 | LMNA (0.48) | IDO1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6810302 | 0.80 | CA2 (0.69) | IDO1CA12CA1CA2CA9 | |
| SCHEMBL9703269 | 0.80 | ENPP2 (0.47) | ENPP2TGM2IDO1KDM4EALDH1A1 | |
| SCHEMBL1831690 | 0.80 | ENPP2 (0.46) | ENPP2TGM2IDO1KDM4EALDH1A1 | |
| SCHEMBL9154755 | 0.80 | KDM4E (0.52) | ENPP2TGM2IDO1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28024787 | 0.79 | CA12 (0.61) | ENPP2TGM2ALDH1A1CYP3A4HPGD | |
| SCHEMBL28044035 | 0.79 | ENPP2 (0.50) | ENPP2TGM2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL6517799 | 0.78 | CA2 (0.67) | IDO1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-B1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER (US) | 2004-05-19 | — | — | EP | claimed |