SCHEMBL6807275

SCHEMBL6807275

Cc1nc(C(=O)O)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 12/20 0.46
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
SRD5A2 P31213 1/20 0.44
CNR2 P34972 2/20 0.43
HTT P42858 1/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
CRHBP P24387 1/20 0.42
RAB9A P51151 1/20 0.42
CRHR2 Q13324 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
MARS1 P56192 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6807499 0.79 CNR1 (0.64) CNR1CNR2
SCHEMBL4810834 0.78 PTGS2 (0.42) CNR1KMT2AATMCNR2KDM4E
SCHEMBL6025160 0.78 CNR1 (0.42) CNR1KMT2AATMCNR2
SCHEMBL4807383 0.76 CNR1 (0.53) CNR1SRD5A2CNR2MARS1
SCHEMBL4808460 0.76 CNR1 (0.63) CNR1CNR2
SCHEMBL6024731 0.74 KMT2A (0.47) CNR1KMT2AATM
SCHEMBL3889534 0.73 CNR1 (0.50) CNR1SRD5A2SMN1; SMN2
SCHEMBL3819682 0.72 KMT2A (0.41) CNR1KMT2AATMCNR2
SCHEMBL5986301 0.72 CNR1 (0.72) CNR1CNR2
SCHEMBL5358199 0.71 CNR1 (0.70) CNR1SRD5A2CNR2MARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040259887-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC 2004-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259887-A1 Cannabinoid receptor ligands and uses thereof CNR1, CNR2, GPR18 CNR1 1/4885KMT2A 3816/4885ATM 4526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.