Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250922 | 0.75 | DGAT1 (0.41) | DGAT1CA12CA14 | |
| SCHEMBL4449736 | 0.71 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL4448260 | 0.71 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL5895740 | 0.70 | DGAT1 (0.44) | DGAT1CA12CA14 | |
| SCHEMBL5895747 | 0.70 | DGAT1 (0.44) | DGAT1CA12CA14 | |
| SCHEMBL10892362 | 0.69 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL1061233 | 0.69 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL2141980 | 0.68 | DGAT1 (0.54) | DGAT1CA12CA14 | |
| SCHEMBL27765256 | 0.68 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL16171890 | 0.67 | CA1 (0.36) | DGAT1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132784-A1 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132784-A1 | Amino alcohol derivatives | CD4, ADH1C, ADH1A | DGAT1 2640/4885CA12 2546/4885CA14 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.