SCHEMBL6807411

SCHEMBL6807411

Nc1ccc(Oc2ccc(N)cc2O)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 1/20 0.52
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MAPT P10636 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MITF O75030 1/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
NLRP1 Q9C000 1/20 0.47
NOD2 Q9HC29 1/20 0.47
PDE7A Q13946 2/20 0.46
TTR P02766 2/20 0.46
MAOA P21397 1/20 0.45
PNLIP P16233 1/20 0.45
TEAD4 Q15561 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2941282 0.92 MEN1 (0.48) ALDH1A1CYP3A4TSHRTDP1MEN1
SCHEMBL5548962 0.88 TTR (0.61) CYP3A4MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL2829833 0.88 ALDH1A1 (0.48) ALDH1A1CYP3A4TSHRTDP1MAPT
SCHEMBL1347657 0.87 CASP1 (0.50) ALDH1A1CYP3A4TSHRTDP1MAPT
SCHEMBL5607469 0.85 TEAD4 (0.57) ALDH1A1CYP3A4TSHRTDP1MAPT
SCHEMBL712623 0.85 CYP3A4 (0.41) ALDH1A1CYP3A4TSHRMAPTMEN1
SCHEMBL31510866 0.85 CYP3A4 (0.41) ALDH1A1CYP3A4TSHRMAPTMEN1
SCHEMBL7555563 0.85 TTR (0.53) ALDH1A1CYP3A4TSHRTDP1MAPT
SCHEMBL7026614 0.81 NCOA1 (0.58) ALDH1A1CYP3A4TSHRTDP1MAPT
SCHEMBL20132295 0.81 ALDH1A1 (0.56) ALDH1A1CYP3A4TSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040082732-A1 Crosslinkable oligoimides FRANCE TELECOM (FR) 2004-04-29 US claimed
WO-2021028960-A1 COLORED RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE 太陽ホールディングス株式会社 2021-02-18 WO disclosed
WO-2021029243-A1 COLORED RESIN COMPOSITION, CURED PRODUCT AND LAMINATE 太陽ホールディングス株式会社 2021-02-18 WO disclosed
US-20040082732-A1 Crosslinkable oligoimides FRANCE TELECOM (FR) 2004-04-29 US disclosed
EP-0291779-A2 Heat-resistant positive resist, and process for the production of heat-resistant resist patterns SIEMENS AKTIENGESELLSCHAFT (DE) 1988-11-23 EP disclosed