Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PNLIP | P16233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807411 | 0.92 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1CYP3A4TTR | |
| SCHEMBL712623 | 0.85 | CYP3A4 (0.41) | MEN1KMT2AALDH1A1CYP3A4ALOX15 | |
| SCHEMBL31510866 | 0.85 | CYP3A4 (0.41) | MEN1KMT2AALDH1A1CYP3A4ALOX15 | |
| SCHEMBL7024360 | 0.85 | ALDH1A1 (0.50) | MEN1KMT2AESR1ESR2TAAR5 | |
| SCHEMBL5548962 | 0.85 | TTR (0.61) | MEN1KMT2ACYP3A4TTR | |
| SCHEMBL676467 | 0.84 | MEN1 (0.56) | MEN1KMT2AESR1ESR2TAAR5 | |
| SCHEMBL1347657 | 0.83 | CASP1 (0.50) | MEN1KMT2AESR2ALDH1A1CYP3A4 | |
| SCHEMBL28572686 | 0.81 | TAAR5 (0.65) | MEN1KMT2AESR1ESR2TAAR5 | |
| SCHEMBL13683235 | 0.81 | PDE10A (0.47) | MEN1KMT2AESR1ESR2TAAR5 | |
| SCHEMBL10703684 | 0.81 | PDE7A (0.53) | MEN1KMT2AESR1ESR2TAAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4505332-B2 | — | — | 2010-07-21 | — | — | JP | claimed |
| US-20060120957-A1 | Radioactive transition metal-imido hetero-diphosphine complexes, their preparation and radiopharmaceutical compositions thereof | BRACCO IMAGING S.P.A. (IT) | 2006-06-08 | — | — | US | claimed |
| EP-1560602-B1 | RADIOACTIVE TRANSITION METAL-IMIDO HETERO-DIPHOSPHINE COMPLEXES, THEIR PREPARATION AND RADIOPHARMACEUTICAL COMPOSITIONS THEREOF | BRACCO IMAGING SPA (IT) | 2006-04-12 | — | — | EP | claimed |
| JP-2006505599-A | — | — | 2006-02-16 | — | — | JP | claimed |
| EP-1560602-A1 | RADIOACTIVE TRANSITION METAL-IMIDO HETERO-DIPHOSPHINE COMPLEXES, THEIR PREPARATION AND RADIOPHARMACEUTICAL COMPOSITIONS THEREOF | Bracco Imaging S.p.A. (IT) | 2005-08-10 | — | — | EP | claimed |
| WO-2004041311-A1 | RADIOACTIVE TRANSITION METAL-IMIDO HETERO-DIPHOSPHINE COMPLEXES, THEIR PREPARATION AND RADIOPHARMACEUTICAL COMPOSITIONS THEREOF | BRACCO IMAGING S.P.A. (IT) | 2004-05-21 | — | — | WO | claimed |
| EP-1417977-A1 | Radioactive transition metal-imido hetero-diphosphine complexes, their preparation and radiopharmaceutical compositions thereof | BRACCO IMAGING S.p.A. (IT) | 2004-05-12 | — | — | EP | claimed |
| US-7771704-B2 | Radioactive transition metal-imido hetero-diphosphine complexes, their preparation and radiopharmaceutical compositions thereof | BRACCO IMAGING S.P.A. (IT) | 2010-08-10 | — | — | US | disclosed |
| US-20080267869-A1 | RADIOACTIVE TRANSITION METAL-IMIDO HETERO-DIPHOSPHINE COMPLEXES, THEIR PREPARATION AND RADIOPHARMACEUTICAL COMPOSITIONS THEREOF | BRACCO IMAGING S.P.A. (IT) | 2008-10-30 | — | — | US | disclosed |
| US-20060120957-A1 | Radioactive transition metal-imido hetero-diphosphine complexes, their preparation and radiopharmaceutical compositions thereof | BRACCO IMAGING S.P.A. (IT) | 2006-06-08 | — | — | US | disclosed |
| EP-1560602-B1 | RADIOACTIVE TRANSITION METAL-IMIDO HETERO-DIPHOSPHINE COMPLEXES, THEIR PREPARATION AND RADIOPHARMACEUTICAL COMPOSITIONS THEREOF | BRACCO IMAGING SPA (IT) | 2006-04-12 | — | — | EP | disclosed |
| EP-1560602-A1 | RADIOACTIVE TRANSITION METAL-IMIDO HETERO-DIPHOSPHINE COMPLEXES, THEIR PREPARATION AND RADIOPHARMACEUTICAL COMPOSITIONS THEREOF | Bracco Imaging S.p.A. (IT) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041311-A1 | RADIOACTIVE TRANSITION METAL-IMIDO HETERO-DIPHOSPHINE COMPLEXES, THEIR PREPARATION AND RADIOPHARMACEUTICAL COMPOSITIONS THEREOF | BRACCO IMAGING S.P.A. (IT) | 2004-05-21 | — | — | WO | disclosed |
| EP-1417977-A1 | Radioactive transition metal-imido hetero-diphosphine complexes, their preparation and radiopharmaceutical compositions thereof | BRACCO IMAGING S.p.A. (IT) | 2004-05-12 | — | — | EP | disclosed |
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-6140353-A | USED AS MEDICAMENTS FOR THE TREATMENT AND/OR PREVENTION OF THROMBOSES, APOPLEXY, CARDIAC INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS OR AS ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267869-A1 | RADIOACTIVE TRANSITION METAL-IMIDO HETERO-DIPHOSPHINE COMPLEXES, THEIR PREPARATION AND RADIOPHARMACEUTICAL COMPOSITIONS THEREOF | MEN1, IGF2R, RABL3 | MEN1 1/4885KMT2A 2640/4885ESR1 1673/4885 |
| US-20060120957-A1 | Radioactive transition metal-imido hetero-diphosphine complexes, their preparation and radiopharmaceutical compositions thereof | RABL3, RABL6, IGF2R | MEN1 6/4885KMT2A 2286/4885ESR1 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.