SCHEMBL6807596

SCHEMBL6807596

O=C(c1ncc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1)N1CCCCC1

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 11/20 0.71
CNR2 P34972 3/20 0.53
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
ALPL P05186 2/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6025614 0.90 CNR1 (0.58) CNR1CNR2
SCHEMBL6025796 0.90 CNR1 (0.58) CNR1CNR2RAB9AALPLKMT2A
SCHEMBL6025648 0.89 CNR1 (0.56) CNR1CNR2ALPL
SCHEMBL6026092 0.89 CNR1 (0.56) CNR1NPC1RAB9AALPLMEN1
SCHEMBL6025823 0.89 CNR1 (0.56) CNR1CNR2
SCHEMBL6025806 0.88 CNR1 (0.56) CNR1CNR2
SCHEMBL6026396 0.86 ALPL (0.54) CNR1ALPL
SCHEMBL6025602 0.86 CNR1 (0.53) CNR1CNR2
SCHEMBL6812212 0.86 SLC6A7 (0.55) CNR1MEN1KMT2A
SCHEMBL6025637 0.85 CNR1 (0.53) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040259887-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC 2004-12-23 US claimed
US-20040259887-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC 2004-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259887-A1 Cannabinoid receptor ligands and uses thereof CNR1, CNR2, GPR18 CNR1 1/4885CNR2 2/4885NPC1 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.