Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 5/20 | 0.45 |
| ▸ | CDK8 | P49336 | 5/20 | 0.45 |
| ▸ | CDC7 | O00311 | 3/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | CHUK | O15111 | 3/20 | 0.41 |
| ▸ | IKBKB | O14920 | 3/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803393 | 0.87 | FTO (0.44) | CCNCCDK8CDC7FTOCHUK | |
| SCHEMBL4437714 | 0.74 | CHUK (0.59) | CCNCCDK8CDC7CHUKIKBKB | |
| SCHEMBL6806730 | 0.73 | ALOX15 (0.35) | — | |
| SCHEMBL7620819 | 0.71 | PTGS1 (0.45) | — | |
| SCHEMBL28229035 | 0.70 | BACE1 (0.37) | — | |
| SCHEMBL61963 | 0.69 | AAK1 (0.53) | CHUKAAK1CYP17A1 | |
| SCHEMBL7619226 | 0.67 | AKR1C3 (0.40) | CCNCCDK8CDC7CHUKIKBKB | |
| SCHEMBL18717123 | 0.67 | ERN1 (0.48) | CDC7FTOCHUKIKBKBIKBKE | |
| SCHEMBL25138862 | 0.66 | CDC7 (0.43) | CCNCCDK8CDC7LRRK2CHUK | |
| SCHEMBL933898 | 0.66 | CYP17A1 (0.49) | CCNCCDK8LRRK2CHUKAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | MAETZKE THOMAS (CH) | 2004-10-07 | — | — | US | disclosed |
| EP-1183317-B1 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6552187-B1 | Cyclization condensation of arylmalonic acid diamides or arylmalonic acid monoamides with hydrazine derivatives forming substituted 3-hydroxy-4-aryl-5-oxopyrazolines; high yield and purity | SYNGENTA CROP PROTECTION, INC. | 2003-04-22 | — | — | US | disclosed |
| EP-1183317-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | Syngenta Participations AG (CH) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000078881-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | CBR3, CBR1, CYC1 | CCNC 81/4885CDK8 3217/4885CDC7 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.