Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | KHK | P50053 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812356 | 0.91 | ALDH1A1 (0.49) | ALDH1A1LMNAHTR2CBCL2A1HTR6 | |
| SCHEMBL4247507 | 0.84 | HTR2C (0.45) | ALDH1A1LMNAHTR2CHTR6KHK | |
| SCHEMBL4247502 | 0.84 | HTR2C (0.45) | ALDH1A1LMNAHTR2CHTR6KHK | |
| SCHEMBL6811561 | 0.79 | AR (0.58) | — | |
| SCHEMBL4244446 | 0.79 | HTR6 (0.61) | ALDH1A1LMNAHTR2CHTR6KHK | |
| SCHEMBL4244450 | 0.79 | HTR6 (0.61) | ALDH1A1LMNAHTR2CHTR6KHK | |
| SCHEMBL4247868 | 0.79 | HTR6 (0.61) | ALDH1A1LMNAHTR2CHTR6KHK | |
| SCHEMBL1901039 | 0.77 | ALDH1A1 (0.63) | ALDH1A1LMNAHTR2CBCL2A1HTR6 | |
| SCHEMBL1904488 | 0.77 | ALDH1A1 (0.63) | ALDH1A1LMNAHTR2CBCL2A1HTR6 | |
| SCHEMBL1901041 | 0.77 | ALDH1A1 (0.63) | ALDH1A1LMNAHTR2CBCL2A1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-06-24 | — | — | US | disclosed |
| EP-1345930-A2 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050067-A2 | PHARMACEUTICAL HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | CYP2D6, LPXN, CYP1B1 | ALDH1A1 1563/4885LMNA 1448/4885HTR2C 1211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.