Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808332 | 0.91 | ALDH1A1 (0.52) | ALDH1A1LMNAADRB1HTR2CBCL2A1 | |
| SCHEMBL30890968 | 0.85 | DRD2 (0.61) | ALDH1A1LMNAADRB1DRD2DRD3 | |
| SCHEMBL24719093 | 0.85 | DRD2 (0.61) | ALDH1A1LMNAADRB1DRD2DRD3 | |
| SCHEMBL24719092 | 0.85 | DRD2 (0.61) | ALDH1A1LMNAADRB1DRD2DRD3 | |
| SCHEMBL4244450 | 0.82 | HTR6 (0.61) | ALDH1A1LMNAHTR2CPRKCQPRKCD | |
| SCHEMBL4244446 | 0.82 | HTR6 (0.61) | ALDH1A1LMNAHTR2CPRKCQPRKCD | |
| SCHEMBL4247868 | 0.82 | HTR6 (0.61) | ALDH1A1LMNAHTR2CPRKCQPRKCD | |
| SCHEMBL5362957 | 0.78 | ADRB1 (0.70) | ALDH1A1LMNAADRB1DRD2DRD3 | |
| SCHEMBL4247502 | 0.78 | HTR2C (0.45) | ALDH1A1LMNAADRB1HTR2CPRKCQ | |
| SCHEMBL4247507 | 0.78 | HTR2C (0.45) | ALDH1A1LMNAADRB1HTR2CPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | CYP2D6, LPXN, CYP1B1 | ALDH1A1 1563/4885LMNA 1448/4885ADRB1 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.