SCHEMBL6808538

SCHEMBL6808538

OC(c1ccc(C(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)(C(F)(F)F)C(F)(F)F)cc1)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.61
ESR2 Q92731 1/20 0.61
NR1H2 P55055 14/20 0.58
NR1H3 Q13133 14/20 0.58
MLYCD O95822 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131990 0.89 NR1H2 (0.68) NR1H2NR1H3MLYCDSMN1; SMN2
Water SCHEMBL1684070 0.86 NR1H2 (0.65) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL18716 0.82 NR1H2 (0.56) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL24901413 0.81 NR1H2 (0.61) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL9621271 0.81 NR1H2 (0.60) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL8021367 0.79 NR1H2 (0.58) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL1516045 0.79 ESR1 (0.61) ESR1ESR2NR1H2NR1H3MLYCD
SCHEMBL19224 0.77 NR1H2 (0.56) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL14593303 0.77 NR1H2 (0.61) ESR1ESR2NR1H2NR1H3MLYCD
SCHEMBL17054 0.77 NR1H2 (0.56) NR1H2NR1H3MLYCDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169869-B2 Polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-01-30 US disclosed
US-7169869-B2 Polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-01-30 US disclosed
US-20040122179-A1 Structures providing low absorbing polymers at 157 nm wavelengths CORNELL RESEARCH FOUNDATION, INC. 2004-06-24 US disclosed