SCHEMBL24901413

SCHEMBL24901413

OC(c1ccc(C(F)(F)F)cc1)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 11/20 0.61
NR1H3 Q13133 11/20 0.61
RORC P51449 1/20 0.60
MLYCD O95822 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
AR P10275 1/20 0.48
EPHX2 P34913 1/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
ORAI1 Q96D31 1/20 0.48
ORAI2 Q96SN7 1/20 0.48
ORAI3 Q9BRQ5 1/20 0.48
TRPV6 Q9H1D0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131990 0.91 NR1H2 (0.68) NR1H2NR1H3MLYCDSMN1; SMN2
Water SCHEMBL1684070 0.88 NR1H2 (0.65) NR1H2NR1H3MLYCDSMN1; SMN2AR
SCHEMBL9621271 0.83 NR1H2 (0.60) NR1H2NR1H3RORCMLYCDSMN1; SMN2
SCHEMBL8021367 0.81 NR1H2 (0.58) NR1H2NR1H3RORCMLYCDSMN1; SMN2
SCHEMBL1516045 0.81 ESR1 (0.61) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL6808538 0.81 ESR1 (0.61) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL17054 0.79 NR1H2 (0.56) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL14593303 0.79 NR1H2 (0.61) NR1H2NR1H3MLYCDSMN1; SMN2AR
SCHEMBL128398 0.79 NR1H2 (0.56) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL24245843 0.79 NR1H2 (0.56) NR1H2NR1H3MLYCDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed
US-20230019681-A1 POSITIVE RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS HNRNPU, EWSR1, HNRNPR NR1H2 3896/4885NR1H3 3340/4885RORC 3434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.