SCHEMBL6808713

SCHEMBL6808713

COc1ccc(O)c(NS(=O)(=O)c2ccccc2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.64
GFER P55789 2/20 0.64
APOBEC3G Q9HC16 1/20 0.64
ALDH1A1 P00352 3/20 0.63
TP53 P04637 2/20 0.63
MAPT P10636 2/20 0.63
MITF O75030 1/20 0.63
LMNA P02545 1/20 0.63
THRB P10828 1/20 0.63
HPGD P15428 1/20 0.63
ALOX15 P16050 1/20 0.63
CASP1 P29466 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
HKDC1 Q2TB90 1/20 0.63
HSD17B10 Q99714 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
KEAP1 Q14145 4/20 0.58
NFE2L2 Q16236 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7176816 0.91 LMNA (0.66) GAAGFERALDH1A1TP53MAPT
SCHEMBL9771526 0.84 GAA (0.62) GAAGFERAPOBEC3GALDH1A1TP53
SCHEMBL8752442 0.84 LMNA (0.71) ALDH1A1MAPTLMNAHPGDSMN1; SMN2
SCHEMBL9771521 0.83 GAA (0.61) GAAGFERAPOBEC3GALDH1A1TP53
SCHEMBL3257185 0.82 KEAP1 (0.70) GAAGFERALDH1A1TP53MAPT
SCHEMBL8752407 0.81 LMNA (0.71) ALDH1A1TP53MAPTLMNAL3MBTL1
SCHEMBL12840705 0.80 GAA (0.69) GAAGFERAPOBEC3GALDH1A1MAPT
SCHEMBL6811951 0.80 ADRB3 (0.59)
SCHEMBL7613195 0.78 ADRB3 (0.61)
SCHEMBL9345894 0.78 GAA (1.00) GAAGFERAPOBEC3GALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed