Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5774959 | 0.76 | HTR2C (0.49) | CXCR4SMN1; SMN2POLBHRH3HPGD | |
| SCHEMBL2911347 | 0.75 | HTR2C (0.54) | SMN1; SMN2POLBCYP3A4GAAHTR2C | |
| SCHEMBL29549874 | 0.74 | CYP3A4 (0.44) | SMN1; SMN2POLBCYP3A4HTR2CHTR2B | |
| SCHEMBL23530014 | 0.74 | CYP3A4 (0.44) | SMN1; SMN2POLBCYP3A4HTR2CHTR2B | |
| SCHEMBL16217182 | 0.74 | CYP3A4 (0.41) | SMN1; SMN2POLBCYP3A4HTR2CHTR2B | |
| SCHEMBL14615209 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2HRH3NPC1RAB9AHTR2C | |
| SCHEMBL14615001 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2HRH3NPC1RAB9AHTR2C | |
| SCHEMBL5776366 | 0.71 | CYP3A4 (0.38) | SMN1; SMN2POLBCYP3A4HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL2913328 | 0.71 | HTR2C (0.40) | SMN1; SMN2POLBCYP3A4HTR2CHTR2B | |
| SCHEMBL16168344 | 0.71 | HTR2C (0.44) | SMN1; SMN2POLBCYP3A4HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132728-A1 | Combinations of atorvastatin and alpha1adrenergic receptor antagonists | PFIZER INC | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132728-A1 | Combinations of atorvastatin and alpha1adrenergic receptor antagonists | ADRA1A, ADRA1D, ADRB1 | CXCR4 2551/4885ALOX15 1811/4885SMN1; SMN2 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.