Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.55 |
| ▸ | APOB | P04114 | 7/20 | 0.49 |
| ▸ | MTTP | P55157 | 7/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804769 | 0.89 | MTTP (0.62) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6803858 | 0.83 | SMO (0.52) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6667492 | 0.83 | NOTUM (0.60) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6804621 | 0.82 | SMN1; SMN2 (0.69) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6804308 | 0.82 | RIPK1 (0.45) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6802265 | 0.81 | RIPK1 (0.42) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6805922 | 0.80 | RIPK1 (0.41) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6668770 | 0.80 | SMN1; SMN2 (0.65) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6667781 | 0.80 | NOTUM (0.55) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6668677 | 0.79 | TP53 (0.53) | MAPTSMN1; SMN2TP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | MAPT 4047/4885SMN1; SMN2 1854/4885TP53 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.