Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255088 | 1.00 | ADRB2 (0.44) | ADRB2NFKB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4255087 | 1.00 | ADRB2 (0.44) | ADRB2NFKB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4257700 | 0.91 | ADRB2 (0.49) | ADRB2NFKB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4263998 | 0.91 | ADRB2 (0.49) | ADRB2NFKB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4253565 | 0.91 | ADRB2 (0.46) | ADRB2NFKB1CYP1A2CYP2D6TSHR | |
| SCHEMBL14422856 | 0.91 | ADRB2 (0.46) | ADRB2NFKB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4253746 | 0.87 | ADRB2 (0.52) | ADRB2ADRB1 | |
| SCHEMBL4256408 | 0.86 | ADRB3 (0.37) | ADRB2ADRB1CASP3CASP6ADRB3 | |
| SCHEMBL6919440 | 0.86 | ADRB3 (0.37) | ADRB2ADRB1CASP3CASP6ADRB3 | |
| SCHEMBL4256407 | 0.86 | ADRB3 (0.37) | ADRB2ADRB1CASP3CASP6ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229904-A1 | Compounds useful for the treatment of diseases | PFIZER INC | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229904-A1 | Compounds useful for the treatment of diseases | LTC4S, CYP11B1, CYP11B2 | ADRB2 901/4885NFKB1 320/4885CYP1A2 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.