SCHEMBL6809277

SCHEMBL6809277

COC(=O)c1ccccc1OC(=O)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.72
MAPT P10636 4/20 0.62
PRSS1 P07477 1/20 0.61
ACR P10323 1/20 0.61
NPSR1 Q6W5P4 2/20 0.59
KMT2A Q03164 3/20 0.57
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
HTT P42858 1/20 0.52
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.47
NPY1R P25929 1/20 0.47
NPY2R P49146 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ELANE P08246 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6813193 0.89 SLC6A3 (0.90) SLC6A3MAPTPRSS1ACRKMT2A
SCHEMBL5706100 0.89 SLC6A3 (0.73) SLC6A3MAPTPRSS1ACRNPSR1
SCHEMBL5706076 0.88 SLC6A3 (0.87) SLC6A3MAPTPRSS1ACRKMT2A
SCHEMBL8768802 0.87 NPSR1 (0.58) SLC6A3MAPTPRSS1ACRNPSR1
SCHEMBL6813163 0.85 NPSR1 (0.56) SLC6A3MAPTPRSS1ACRNPSR1
SCHEMBL30373246 0.84 SLC6A3 (1.00) SLC6A3MAPTPRSS1ACRNPSR1
SCHEMBL2284514 0.84 SLC6A3 (1.00) SLC6A3MAPTPRSS1ACRNPSR1
SCHEMBL7615922 0.83 SLC6A3 (0.79) SLC6A3MAPTPRSS1ACRKMT2A
SCHEMBL7871178 0.83 SLC6A3 (0.84) SLC6A3MAPTPRSS1ACRKMT2A
SCHEMBL6812283 0.83 SLC6A3 (0.79) SLC6A3MAPTPRSS1ACRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed