SCHEMBL8768802

SCHEMBL8768802

CC(=O)c1ccccc1OC(=O)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.58
MAPT P10636 5/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
SLC6A3 Q01959 1/20 0.53
KMT2A Q03164 3/20 0.52
TNF P01375 1/20 0.47
KLF5 Q13887 1/20 0.47
NOD1 Q9Y239 1/20 0.47
PRSS1 P07477 3/20 0.46
ACR P10323 3/20 0.46
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
HSD17B10 Q99714 1/20 0.45
NR1H4 Q96RI1 1/20 0.45
ELANE P08246 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8768780 0.87 KMT2A (0.51) NPSR1MAPTTDP1L3MBTL1SLC6A3
SCHEMBL6809277 0.87 SLC6A3 (0.72) NPSR1MAPTTDP1L3MBTL1SLC6A3
SCHEMBL26490187 0.84 SLC6A3 (0.72) NPSR1MAPTTDP1SLC6A3KMT2A
SCHEMBL5228556 0.84 KMT2A (0.62) NPSR1MAPTTDP1L3MBTL1SLC6A3
SCHEMBL8391960 0.83 NPSR1 (0.56) NPSR1MAPTTDP1L3MBTL1KMT2A
SCHEMBL6813163 0.83 NPSR1 (0.56) NPSR1MAPTTDP1L3MBTL1SLC6A3
SCHEMBL7592511 0.83 SLC6A3 (0.57) MAPTSLC6A3KMT2APRSS1ACR
SCHEMBL8391961 0.82 NPSR1 (0.55) NPSR1MAPTTDP1L3MBTL1SLC6A3
SCHEMBL13292741 0.80 NPSR1 (0.59) NPSR1MAPTTDP1L3MBTL1SLC6A3
SCHEMBL5706010 0.80 NPSR1 (0.59) NPSR1MAPTTDP1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659738-B1 N-(Carbonyl, carbonimidoyl, carbonothioyl) sulfonamide charge control agents and toners and developers EASTMAN KODAK CO (US) 1997-09-10 EP disclosed
US-5616797-A USED IN ELECTROPHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1997-04-01 US disclosed
US-5523484-A DI- OR TRI-CARBONYL SULFONAMIDO-PHENYL COMPOUNDS AS CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1996-06-04 US disclosed
EP-0659738-A1 N-(Carbonyl, carbonimidoyl, carbonothioyl) sulfonamide charge control agents and toners and developers EASTMAN KODAK COMPANY (US) 1995-06-28 EP disclosed
US-5405727-A Electrophotography EASTMAN KODAK COMPANY (US) 1995-04-11 US disclosed
US-5385800-A A metal-free, colorless, heat resistant controllers EASTMAN KODAK COMPANY (US) 1995-01-31 US disclosed