Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599002 | 0.85 | KDM4E (0.54) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL11622271 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL1985401 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL26963087 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL15346268 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL27456673 | 0.80 | KMT2A (0.53) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL28328240 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL10547837 | 0.79 | L3MBTL1 (0.47) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL7423312 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL27379526 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TDP1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014161-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2004-01-22 | — | — | US | disclosed |