Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809339 | 0.85 | ALDH1A1 (0.50) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL20591992 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11622271 | 0.81 | ALDH1A1 (0.56) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6443734 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL57737 | 0.80 | ALDH1A1 (0.58) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL57738 | 0.80 | ALDH1A1 (0.58) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL8543190 | 0.79 | ALDH1A1 (0.50) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL27149163 | 0.79 | ALDH1A1 (0.44) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL10547837 | 0.78 | L3MBTL1 (0.47) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| Bicarbonate SCHEMBL18955379 | 0.78 | ALDH1A1 (0.56) | KDM4EALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| US-6127414-A | NPY antagonists | ASTRA AKTIEBOLAG (SE) | 2000-10-03 | — | — | US | disclosed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |