Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809826 | 1.00 | MAOA (0.61) | MAOAPTGS1MTNR1AMTNR1BMEN1 | |
| SCHEMBL21547285 | 0.82 | MAPK1 (0.53) | MTNR1AMTNR1BKMT2AMAPK1 | |
| SCHEMBL13212031 | 0.77 | MAOA (0.69) | MAOAPTGS1MTNR1AMTNR1BMEN1 | |
| SCHEMBL11598862 | 0.77 | MAOA (0.69) | MAOAPTGS1MTNR1AMTNR1BMEN1 | |
| SCHEMBL3961897 | 0.76 | SCN4A (0.54) | MAOAMEN1KMT2ATAAR1LMNA | |
| SCHEMBL13996939 | 0.76 | MAOA (0.67) | MAOAPTGS1MTNR1AMTNR1BMEN1 | |
| SCHEMBL96547 | 0.76 | LMNA (0.57) | MAOAPTGS1MTNR1AMTNR1BMEN1 | |
| SCHEMBL11573929 | 0.76 | CYP2D6 (0.67) | PTGS1MEN1KMT2ACYP2D6ADRB2 | |
| Phenoxypropazine SCHEMBL147198 | 0.76 | MAOA (1.00) | MAOAPTGS1MTNR1AMTNR1BMEN1 | |
| Phenoxypropazine SCHEMBL4034660 | 0.74 | MAOA (0.96) | MAOAPTGS1MTNR1AMTNR1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | MAOA 3774/4885PTGS1 1789/4885MTNR1A 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.