Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 5/20 | 0.55 |
| ▸ | PYGL | P06737 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.49 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.49 |
| ▸ | PRKX | P51817 | 1/20 | 0.49 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.49 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814426 | 1.00 | CTRB1 (0.55) | CTRB1PYGLROCK2ROCK1NPC1 | |
| SCHEMBL6500684 | 0.86 | CTRB1 (0.54) | CTRB1PYGLNPC1RAB9APIN1 | |
| SCHEMBL7310941 | 0.86 | BACE1 (0.56) | CTRB1 | |
| SCHEMBL6501344 | 0.86 | CTRB1 (0.54) | CTRB1PYGLNPC1RAB9APIN1 | |
| SCHEMBL6931878 | 0.85 | CTRB1 (0.59) | CTRB1NPC1RAB9APIN1CTSL | |
| SCHEMBL8577646 | 0.85 | NPC1 (0.53) | CTRB1NPC1RAB9ACTSLCTSS | |
| SCHEMBL14425866 | 0.84 | CTRB1 (0.51) | CTRB1NPC1RAB9APIN1CTSL | |
| SCHEMBL7433925 | 0.83 | CTRB1 (0.56) | CTRB1PYGLNPC1RAB9APIN1 | |
| SCHEMBL7432804 | 0.83 | CTRB1 (0.56) | CTRB1PYGLNPC1RAB9APIN1 | |
| SCHEMBL8758974 | 0.83 | CTRB1 (0.56) | CTRB1PYGLNPC1RAB9APIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052257-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-3-AMINO-1,2-EPOXY COMPOUNDS | NIPPON KAYAKU KK (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6452026-B1 | REACTING THREO-3-AMINO-1,2-DIOL COMPOUND WITH SULFONYLATING AGENT AND EPOXIDATION TO FORM 3-AMINO-1,2-EPOXY COMPOUND | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-09-17 | — | — | US | disclosed |
| US-20020058825-A1 | Process for producing optically active threo-3-amino-1,2-epoxy compounds | SAGAWA YUKIHIRO (JP) | 2002-05-16 | — | — | US | disclosed |
| US-6376685-B1 | SULFONYLATION; CYCLIZATION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1052257-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-3-AMINO-1,2-EPOXY COMPOUNDS | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058825-A1 | Process for producing optically active threo-3-amino-1,2-epoxy compounds | DAO, DHPS, ALKBH3 | CTRB1 3149/4885PYGL 2650/4885ROCK2 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.