Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 10/20 | 0.56 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18740554 | 0.93 | BACE1 (0.67) | BACE1SLC6A11BCHE | |
| SCHEMBL8577646 | 0.90 | NPC1 (0.53) | BACE1SLC6A11CTRB1 | |
| SCHEMBL6809872 | 0.86 | CTRB1 (0.55) | CTRB1 | |
| SCHEMBL6814426 | 0.86 | CTRB1 (0.55) | CTRB1 | |
| Hydrochloric Acid SCHEMBL5387276 | 0.86 | BACE1 (0.51) | BACE1SLC6A11BCHE | |
| SCHEMBL7306846 | 0.86 | BACE1 (0.60) | BACE1SLC6A11BCHE | |
| SCHEMBL7305633 | 0.86 | BACE1 (0.60) | BACE1SLC6A11BCHE | |
| SCHEMBL6501344 | 0.85 | CTRB1 (0.54) | BACE1CTRB1 | |
| SCHEMBL6500684 | 0.85 | CTRB1 (0.54) | BACE1CTRB1 | |
| SCHEMBL6931878 | 0.84 | CTRB1 (0.59) | CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559256-A | Aminediol protease inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0580402-A2 | Aminediol protease inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1994-01-26 | — | — | EP | disclosed |